Publications

Here are some highlights of our publications followed by all our publications below.

(^* = equal contribution, ⁺ = corresponding authors)

Highlighted

Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates

Elena Camacho-Aguilar⁺, Sumin Yoon, Miguel A. Ortiz-Salazar, Siqi Du, M. Cecilia Guerra, Aryeh Warmflash⁺

Cell Systems   ·   15 May 2024   ·   doi:10.1016/j.cels.2024.04.001

Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions

Meritxell Saez^*, Robert Blassberg^*, Elena Camacho-Aguilar^*, Eric D. Siggia, David A. Rand⁺, James Briscoe⁺

Cell Systems   ·   01 Jan 2022   ·   doi:10.1016/j.cels.2021.08.013

Quantifying cell transitions in C. elegans with data-fitted landscape models

Elena Camacho-Aguilar⁺, Aryeh Warmflash, David A. Rand⁺

PLOS Computational Biology   ·   01 Jun 2021   ·   doi:10.1371/journal.pcbi.1009034

All

2024

Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates

Elena Camacho-Aguilar⁺, Sumin Yoon, Miguel A. Ortiz-Salazar, Siqi Du, M. Cecilia Guerra, Aryeh Warmflash⁺

Cell Systems   ·   15 May 2024   ·   doi:10.1016/j.cels.2024.04.001

Endogenous Nodal switches Wnt interpretation from posteriorization to germ layer differentiation in geometrically constrained human pluripotent cells

Miguel Angel Ortiz-Salazar, Elena Camacho-Aguilar, Aryeh Warmflash

Pre-print on bioRxiv   ·   14 Mar 2024   ·   doi:10.1101/2024.03.13.584912

2022

Combinatorial interpretation of BMP and WNT allows BMP to act as a morphogen in time but not in concentration

Elena Camacho-Aguilar⁺, Sumin Yoon, Miguel A. Ortiz-Salazar, Aryeh Warmflash⁺

Pre-print on bioRxiv   ·   12 Nov 2022   ·   doi:10.1101/2022.11.11.516212

Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR

Emily Sempou, Valentyna Kostiuk, Jie Zhu, M. Cecilia Guerra, Leonid Tyan, ..., Michael J. Caplan, David Zenisek, Aryeh Warmflash, Nick D. L. Owens, Mustafa K. Khokha

Nature Communications   ·   05 Nov 2022   ·   doi:10.1038/s41467-022-34363-w

Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions

Meritxell Saez^*, Robert Blassberg^*, Elena Camacho-Aguilar^*, Eric D. Siggia, David A. Rand⁺, James Briscoe⁺

Cell Systems   ·   01 Jan 2022   ·   doi:10.1016/j.cels.2021.08.013

2021

Quantifying cell transitions in C. elegans with data-fitted landscape models

Elena Camacho-Aguilar⁺, Aryeh Warmflash, David A. Rand⁺

PLOS Computational Biology   ·   01 Jun 2021   ·   doi:10.1371/journal.pcbi.1009034

A quantitative landscape of cell fate transitions identifies principles of cellular decision-making

Meritxell Saez^*, Robert Blassberg^*, Elena Camacho-Aguilar^*, Eric D. Siggia, David A. Rand⁺, James Briscoe⁺

Pre-print on bioRxiv   ·   11 Mar 2021   ·   doi:10.1101/2021.03.11.434982

Quantifying cell transitions in C. elegans with data-fitted landscape models

Elena Camacho-Aguilar⁺, Aryeh Warmflash, David A. Rand⁺

Pre-print on bioRxiv   ·   22 Jan 2021   ·   doi:10.1101/2021.01.22.426019

2020

Insights into mammalian morphogen dynamics from embryonic stem cell systems

Elena Camacho-Aguilar, Aryeh Warmflash⁺

Current Topics in Developmental Biology   ·   01 Jan 2020   ·   doi:10.1016/bs.ctdb.2019.11.010